Syncronis HPLC

Syncronis aQ HPLC Columns

Consistent, predictable separations, Column after column, time after time

• Stability in 100% aqueous mobile phase

• Outstanding reproducibility

• Highly pure, high surface area silica

• Highly inert towards basic compounds

• Rigorously tested to ensure quality

 Specifications

 Stability in 100% aqueous mobile phase

In comparison to a conventionally endcapped C18, the Thermo Scientific™ Syncronis™

aQ polar end-capped C18 stationary phase exhibits superior stability towards aqueous mobile phase.

Syncronis aQ shows no degradation in performance after 100 injections in a buffered 100% aqueous eluent.

Application: Amoxicillin and Potassium Clavulanate (USP)

 Syncronis C8 HPLC Columns

 Consistent, predictable separations,Column after column, time after time

 • Outstanding reproducibility

 • Highly pure, high surface area silica

 • Less hydrophobic than C18

 •  Double endcapped for extra surface coverage

 •  Highly inert towards basic compounds

 •  Rigorously tested to ensure quality

 Specifications

 Less retentive than C18

Thermo Scientific™ Syncronis™ C8 HPLC columns are less hydrophobic than the C18 and are therefore particularly useful where the lesser degree of hydrophobicity is needed in order to successfully retain compounds of interest. Syncronis C8 HPLC columns can also be used where it is desirable to elute compounds more quickly than with a C18 HPLC column.

 Application: Fenoprofen (USP)

  Application: Uron Herbicides

Syncronis C18 HPLC Columns

Consistent, predictable separations, Column after column, time after time

•  Outstanding reproducibility

•  Highly pure, high surface area silica

•  High carbon load for increased retention

•  Double endcapped for extra surface coverage

• Highly inert towards basic compounds

• Rigorously tested to ensure quality

  Specifications

Outstanding column to column reproducibility

When developing a new method, one of the most important goals for the chromatographer is to achieve a consistent, reproducible separation. The selection of a highly reproducible HPLC column is essential if this goal is to be attained.

Thermo Scientific™ Syncronis™ C18 HPLC columns show excellent column to column reproducibility, as illustrated here by the analysis of zidovudine using five separate columns.

The reproducibility in terms of retention time and peak area is less than or equal to 0.5%, column to column. This indicates that the columns are well packed.

The variation in peak area is 0.27%, which is important for quantitation of analytes.

Syncronis C18 HPLC columns achieve this goal, starting from the highly pure, high surface area silica and dense bonding, all controlled and characterized through the use of rigorous testing.

New, enhanced, automated column packing methods drive consistency even further and every column is individually tested to ensure that it meets the required specifications.

These extensive testing and quality control procedures ensure the delivery of a consistent product, column after column.